Neil Kelleher

PhD, Cornell University

Interdisciplinary Biological Sciences Program
Department of Molecular Biosciences

Office Phone: 847.467.4362
Kelleher Lab


The Kelleher Group has three primary lines of research focused on Top Down Proteomics, Natural Products Discovery and Biosynthesis and Chromatin Oncobiology and DNA-Damage. An underlying focus, driving all lines of research, is our continued push towards optimizing instrumentation and bioinformatic approaches to best suit the unique needs of a Top Down analysis.


Vellaichamy, A., Tran, J.C., Catherman, A.D., Lee, J.E., Kellie, J.F., Sweet, S.M., Zamdborg, L., Thomas, P.M., Ahlf, D.R., Durbin, K.R., Valaskovic, G.A., Kelleher, N.L. "Size-Sorting Combined with Improved Nanocapillary Liquid Chromatography-Mass Spectrometry for Identification of Intact Proteins up to 80 kDa" Anal. Chem., 2010, 82, 1234-1244.

Li, M., Jiang L., Kelleher, N.L. "Global Histone Profiling by LC-FTMS After Inhibition and Knockdown of Deacetylases in Human Cells" J. Chrom. B., 2009, 877, 3885-3892.

Bumpus, S.B., Evans, B.S., Thomas, P.M., Ntai, I., Kelleher, N.L. "A Proteomics Approach to Discovering Natural Products and Their Biosynthetic Pathways" Nat. Biotechnol., 2009, 27, 951-956.

Lee, J.E., Kellie, J.F., Tran, J.C., Tipton, J.D., Catherman, A.D., Thomas, H.M., Ahlf, D.R., Durbin, K.R., Vellaichamy, A., Ntai, I., Marshall, A.G., Kelleher, N.L. " A Robust Two-Dimensional Separation for Top-Down Tandem Mass Spectrometry of the Low-Mass Proteome" J. Am. Soc. Mass Spectrom., 2009, 20, 2183-2191.


View all publications by publications by Neil L. Kelleher listed in the National Library of Medicine (PubMed).

Recent Photos

April 16, 2015